Water-only Fasting Literature
A database of research publications dating back to 1881!

Latest Research

Author(s): Magowska, A. M.
Publication: Adv Physiol Educ
Publication Year: 2020

The history of hunger is a story about natural disasters and wars, but, on the other hand, also about the investigation of evolutionary defense mechanisms concerning quantitative food shortages. The article presents how fasting and the experimental starving oriented the development of physiology, and it is based on a comparative analysis of monographs and articles on starvation in the medical… Read More

Author(s): Ibrahim, E. M., Al-Foheidi, M. H., Al-Mansour, M. M.
Publication: Support Care Cancer
Publication Year: 2020

Dietary interventions have a significant impact on body metabolism. The sensitivity of cancer cells to nutrient and energy deficiency is an evolving characteristic of cancer biology. Preclinical studies provided robust evidence that energy and caloric restrictions could hinder both cancer growth and progression, besides enhancing the efficacy of chemotherapy and radiation therapy. Moreover,… Read More

Author(s): Liu, B., Hutchison, A. T., Thompson, C. H., Lange, K., Wittert, G. A., Heilbronn, L. K.
Publication: J Clin Endocrinol Metab
Publication Year: 2020

CONTEXT: Impaired lipid metabolism is linked with obesity-associated insulin resistance, which may be reversed by caloric restriction (CR). OBJECTIVE: In a secondary analysis of a randomized controlled trial, we compared the effects of intermittent fasting (IF) and CR on markers of lipid metabolism in muscle. DESIGN: Seventy-six women (BMI 25-40 kg/m2) were randomized to one of three diets for… Read More

Author(s): Fazeli, P. K., Zhang, Y., O'Keefe, J., Pesaresi, T., Lun, M., Lawney, B., Steinhauser, M. L.
Publication: Mol Metab
Publication Year: 2020

OBJECTIVE: The human adaptive fasting response enables survival during periods of caloric deprivation. A crucial component of the fasting response is the shift from glucose metabolism to utilization of lipids, underscoring the importance of adipose tissue as the central lipid-storing organ. The objective of this study was to investigate the response of adipose tissue to a prolonged fast in… Read More

Author(s): Chetiveaux, M., Croyal, M., Ouguerram, K., Fall, F., Flet, L., Zair, Y., Nobecourt, E., Krempf, M.
Publication: Sci Rep
Publication Year: 2020

The aim of this study was to compare the kinetics of apolipoprotein (apo)A-I during fed and fasted states in humans, and to determine to what extent the intestine contributes to apoA-I production. A stable isotope study was conducted to determine the kinetics of apoA-I in prebeta1 high-density lipoprotein (HDL) and alpha-HDL. Six healthy male subjects received a constant intravenous infusion… Read More

Author(s): Alidadi, M., Banach, M., Guest, P. C., Bo, S., Jamialahmadi, T., Sahebkar, A.
Publication: Semin Cancer Biol
Publication Year: 2020

Cancer is one of the most frequent causes of worldwide death and morbidity and is a major public health problem. Although, there are several widely used treatment methods including chemo-, immune- and radiotherapies, these mostly lack sufficient efficiency and induce toxicities in normal surrounding tissues. Thus, finding new approaches to mitigate side effects and potentially accelerate… Read More

Author(s): Fatahi, S., Nazary-Vannani, A., Sohouli, M. H., Mokhtari, Z., Kord-Varkaneh, H., Moodi, V., Tan, S. C., Low, T. Y., Zanghelini, F., Shidfar, F.
Publication: Crit Rev Food Sci Nutr
Publication Year: 2020

Inconsistencies exist with regard to influence of fasting and energy-restricting diets on markers of glucose and insulin controls. To address these controversial, this study was conducted to determine the impact of fasting diets on fasting blood sugars (FBSs), insulin, homeostatic model assessment insulin resistance (HOMA-IR) and hemoglobin A1c (HbA1c) levels. A comprehensive systematic search… Read More

Author(s): Moser, O., Tripolt, N. J., Pferschy, P. N., Obermayer, A., Kojzar, H., Mader, J. K., Brunner, M., Mueller, A., Yildirim, H., Sourij, K., Eckstein, M., Sourij, H.
Publication: American Diabetes Association
Publication Year: 2020

Evidence is accumulating that prolonged fasting (PL) might evoke improvements in metabolic health. Since fasting is accompanied by numerous endogenous processes to equilibrate blood glucose concentration, its feasibility is disputable in people with type 1 diabetes (PWT1D). We aimed to assess the safety and efficacy of PL in c-peptide negative (^< 0.9 ng/mL) PWT1D. Methods: Glucose… Read More

Author(s): Bhootra, K., Bhootra, A. R., Desai, K., Bhootra, R. K., R, M. S.
Publication: J Assoc Physicians India
Publication Year: 2020

Cases have been reported about refeeding syndrome after bariatric surgery for obesity, in head and neck cancer patients, in patients with anorexia nervosa, hyperemesis gravidarum, in persons on hunger strike, malnourished alcoholic persons and persons doing religious fasting. Refeeding after prolonged fasting can cause severe morbidity and even mortality, if not done properly. Depletion of… Read More

Author(s): Myers, T. R., Beauchesne, A. B., Goldhamer, A.C.
Publication: International Journal of Disease Reversal and Prevention
Publication Year: 2020

Fuchs’ endothelial corneal dystrophy (FECD) is a progressive disorder of the corneal endothelium characterized by endothelial cell functional abnormalities and loss of visual acuity. Chronic oxidative stress plays a key role in disease progression. We present the case of a 69-year-old woman with an 18-year history of FECD that improved after dietary intervention with an exclusively whole-plant… Read More