Water-only Fasting Literature
A database of research publications dating back to 1881!

Latest Research

Author(s): Rhule, C, Gabriel, S, Myers, T. R., Goldhamer A.C
Publication: Mary An Liebert INC
Publication Year: 2024

Long COVID is a broad range of symptoms that develop in a subset of people after acute SARS-CoV-2 infection. Current treatment options are investigational, not yet standardized, and aimed at symptomatic management of individual organ systems. This report presents the case of a 73-year-old male patient who achieved sustained improvements in symptoms associated with long COVID after two… Read More

Author(s): Thompson N, NCube M, Gabriel S, Zeiler E, Goldhamer AC
Publication: International Journal of Disease Reversal and Prevention
Publication Year: 2024

Evidence suggests that prolonged water-only fasting is safe and may improve cardiometabolic
biomarkers in normal-weight males, but data in normal-weight females are lacking.
Given the physiological differences between males and females, research is needed
in normal-weight females to assess safety and effectiveness. This article presents preliminary,
Read More

Author(s): Bonjour, M., Gabriel, S., Valencia, A., Goldhamer, A, Myers, T
Publication Year: 2022

Challenging Case in Clinical Practice: Prolonged Water-Only Fasting Followed by an Exclusively Whole-Plant-Food Diet in the Management of Severe Plaque Psoriasis. International Journal of Disease Reversal and Prevention.

Author(s): Sahmla Gabriel, Mackson Ncube, Evelyn Zeiler, Natasha Thompson, Micaela C. Karlsen, David M. Goldman, Zrinka Glavas, Andrew Beauchesne, Eugene Scharf, Alan C. Goldhamer, Toshia R. Myers
Publication: Nutrients
Publication Year: 2022

(1) Background: Chronic inflammation and insulin resistance are associated with cardiometabolic
diseases, such as cardiovascular disease, type 2 diabetes mellitus, and non-alcoholic fatty liver disease. Therapeutic water-only fasting and whole-plant-food refeeding was previously shown to improve markers of cardiometabolic risk and may be an effective preventative treatment but sustained… Read More

Author(s): de Gruil, N., Pijl, H., van der Burg, S., Kroep, J.
Publication: Cancers
Publication Year: 2022

Short-term fasting (STF), using a low caloric, low protein fasting mimicking diet (FMD), appears to be a promising strategy to enhance chemotherapy-based cancer efficacy, while potentially alleviating toxicity. Preclinical results suggest that enhanced tumor immunity and decreased growth signaling, via lowering of circulating insulin and insulin growth factor 1 (IGF-1) levels form the… Read More

Author(s): Bartholomew, C. L., Muhlestein, J. B., Anderson, J. L., May, H. T., Knowlton, K. U., Bair, T. L., Le, V. T., Bailey, B. W., Horne, B. D.
Publication: Eur J Prev Cardiol
Publication Year: 2022

AIMS: Animal models repeatedly show fasting increases longevity. Human data, though, are limited to anecdotal claims. This study evaluated the association of routine fasting with survival and, secondarily, with incident major adverse cardiovascular events. METHODS AND RESULTS: Cardiac catheterization patients enrolled in the Intermountain INSPIRE longitudinal cohort (n = 2785) during 2013-2015… Read More

Author(s): Visioli, F., Mucignat-Caretta, C., Anile, F., Panaite, S. A.
Publication: Nutrients
Publication Year: 2022

Fasting has been practiced for millennia, for religious, ethical, or health reasons. It is also commonplace among different species, from humans, to animals, to lower eukaryotes. Research on fasting is gaining traction based on recent studies that show its role in many adaptive cellular responses such as the reduction of oxidative damage and inflammation, increase of energy metabolism, and in… Read More

Author(s): Thackrey, E., Chen, J., Martino, C. R., Preda, V.
Publication: Nutrition
Publication Year: 2022

With the global rise in obesity and the metabolic syndrome, double diabetes is increasingly prevalent in patients with type 1 diabetes. This review investigated the effects of diet on weight management and metabolic outcomes in patients with double diabetes. MEDLINE, CENTRAL, EMBASE, PsycINFO, CINAHL, ERIC, and Web of Science databases were searched through September 2020. Population- or… Read More

Author(s): Hofer, S. J., Carmona-Gutierrez, D., Mueller, M. I., Madeo, F.
Publication: EMBO Mol Med
Publication Year: 2022

Age-associated diseases are rising to pandemic proportions, exposing the need for efficient and low-cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological levels. While nutrition and health are closely intertwined, our limited understanding of how diet precisely influences disease often precludes the medical use of specific dietary interventions. Caloric… Read More

Author(s): Myers, T, Saul, B, Karlsen, M, Beauchesne, A, Glavas, Z, Ncube, M, Bradley, R, Goldhamer, A
Publication: Cureus
Publication Year: 2022

The overconsumption of calorie-dense foods high in added salt, sugar, and fat is a major contributor to current rates of obesity, and methods to reduce consumption are needed. Prolonged water-only fasting followed by an exclusively whole-plant-food diet free of added salt, oil, and sugar may reduce the consumption of these hyper-palatable foods, but such effects have not been quantified.… Read More