Water-only Fasting Literature
A database of research publications dating back to 1881!

Latest Research

Author(s): Ibrahim, E. M., Al-Foheidi, M. H., Al-Mansour, M. M.
Publication: Support Care Cancer
Publication Year: 2020

Dietary interventions have a significant impact on body metabolism. The sensitivity of cancer cells to nutrient and energy deficiency is an evolving characteristic of cancer biology. Preclinical studies provided robust evidence that energy and caloric restrictions could hinder both cancer growth and progression, besides enhancing the efficacy… Read More

Author(s): Brandhorst, S.
Publication: Geroscience
Publication Year: 2021

The increasingly older population in most developed countries will likely experience aging-related chronic diseases such as diabetes, metabolic syndrome, heart and lung diseases, osteoporosis, arthritis, dementia, and/or cancer. Genetic and environmental factors, but also lifestyle choices including physical activity and dietary habits, play essential roles in disease onset… Read More

Author(s): Alidadi, M., Banach, M., Guest, P. C., Bo, S., Jamialahmadi, T., Sahebkar, A.
Publication: Semin Cancer Biol
Publication Year: 2020

Cancer is one of the most frequent causes of worldwide death and morbidity and is a major public health problem. Although, there are several widely used treatment methods including chemo-, immune- and radiotherapies, these mostly lack sufficient efficiency and induce toxicities in normal surrounding tissues. Thus, finding new approaches to mitigate side effects and potentially… Read More

Author(s): Safdie, F. M., Dorff, T., Quinn, D., Fontana, L., Wei, M., Lee, C., Cohen, P., Longo, V. D.
Publication: Aging (Albany NY)
Publication Year: 2009

Short-term fasting (48 hours) was shown to be effective in protecting normal cells and mice but not cancer cells against high dose chemotherapy, termed Differential Stress Resistance (DSR), but the feasibility and effect of fasting in cancer patients undergoing chemotherapy is unknown. Here we describe 10 cases in which patients diagnosed with a variety of… Read More

Author(s): Plotti, F., Terranova, C., Luvero, D., Bartolone, M., Messina, G., Feole, L., Cianci, S., Scaletta, G., Marchetti, C., Di Donato, V., Fagotti, A., Scambia, G., Benedetti Panici, P., Angioli, R.
Publication: Chemotherapy
Publication Year: 2020

INTRODUCTION: Diet may influence various aspects of human health. In fact, it is well known that diet can favour or not the development of various human pathologies, like diabetes, hypertension, and hypercholesterolaemia. Interestingly, diet has an influence in cancer development too (e.g., this relation has been studied for pancreatic, colonic, gastric, and breast cancers).… Read More

Author(s): Keys, A., Brozek, J., Henschel, A., Mickelsen, O., Longstreet Taylor, H., Simonson, E., Sturgeon Skinner, A., Wells, S. M., Drummond, J. C., Wilder, R. M., King, C. G., Williams, R. R.
Publication: The Biology of Human Starvation
Publication Year: 1950
Author(s): Caffa, I., Nencioni, A.
Publication: Mol Cell Oncol
Publication Year: 2021

We found that periodic fasting increases the anti-cancer activity of endocrine agents used to treat hormone receptor-positive breast cancer and delays acquired resistance to them by reducing blood leptin, insulin and insulin-like growth factor 1 (IGF1). Our work supports further clinical studies of fasting as an adjuvant to endocrine agents in breast Read More

Author(s): Phillips, M. C. L.
Publication: Nutrients
Publication Year: 2019

Fasting is deeply entrenched in evolution, yet its potential applications to today's most common, disabling neurological diseases remain relatively unexplored. Fasting induces an altered metabolic state that optimizes neuron bioenergetics, plasticity, and resilience in a way that may counteract a broad array of neurological disorders. In both animals and humans, fasting prevents and… Read More

Author(s): Benedict, A. L.
Publication: Medical Reviews of Reviews
Publication Year: 1918
Author(s): Dorff, T. B., Groshen, S., Garcia, A., Shah, M., Tsao-Wei, D., Pham, H., Cheng, C. W., Brandhorst, S., Cohen, P., Wei, M., Longo, V., Quinn, D. I.
Publication: BMC Cancer
Publication Year: 2016

BACKGROUND: Short-term starvation prior to chemotherapy administration protects mice against toxicity. We undertook dose-escalation of fasting prior to platinum-based chemotherapy to determine safety and feasibility in cancer patients. METHODS: 3 cohorts fasted before chemotherapy for 24, 48 and 72 h (divided as 48 pre-chemo and 24 post-chemo) and recorded all calories… Read More