Fasting Literature Database

Biomedical publications about prolonged water-only fasting from 1881-1999

TrueNorth Health Foundation has meticulously curated an extensive database of historical literature on prolonged water-only fasting dating back to the late 19th century.

This collection serves as a valuable resource for researchers, healthcare professionals, and individuals interested in exploring early perspectives and research on the effects of water-only fasting in humans.

These publications span a range of topics, including physiological effects, clinical applications, and historical reviews, that offer insights into the rich history and evolving understanding of fasting as a therapeutic intervention.

Role of the kidney in the metabolism of fructose in 60-hour fasted humans

Bjorkman, O., Felig, P.
Diabetes 1982
Abstract

Arterial (A) and renal venous (RV) concentrations and net splanchnic exchange of glucose, fructose, lactate, pyruvate, glycerol, and alanine were studied in the basal state and during a 135-min intravenous infusion of fructose at 2 mmol/min in healthy subjects after a 60-h fast. After 45 min of the fructose infusion, somatostatin (9 microgram/min) was infused for 60 min to induce… Read More

The effect of starvation and refeeding with oral versus intravenous glucose on serum 3,5-,3,3'-and 3'-5'-diiodothyronine and 3'-monoiodothyronine

Jaedig, S., Faber, J.
Acta Endocrinol (Copenh) 1982
Abstract

The effect of complete fasting on the serum concentrations of the iodothyronines 3,5-diiodothyronine (3,5-T2), 3,3'T2, 3', 5'-T2 and 3'-monoiodothyronine (3'-T1) was evaluated. Fourteen obese women underwent a complete fasting for 4 days. Caloric restriction resulted in the following serum hormone levels (before vs 3. day): T4: 103 vs 109 nmol/l (NS), T3: 1.83 vs 1.24… Read More

Urinary excretion of acetylcarnitine during human diabetic and fasting ketosis

Hoppel, C. L., Genuth, S. M.
Am J Physiol 1982
Abstract

The urinary excretion of acetylcarnitine was studied in patients with diabetic ketosis before and during insulin therapy and in normal-weight and obese subjects during fasting. In the diabetic ketotic patients, acetylcarnitine represented 61% of the total acylcarnitine excretion. During the first 24 h of insulin treatment, acetylcarnitine excretion decreased and on the 5th day of treatment was… Read More

Insulin receptor binding and insulin action in human fat cells: effects of obesity and fasting

Pedersen, O., Hjollund, E., Sorensen, N. S.
Metabolism 1982
Abstract

We have studied (125I)-insulin binding and insulin dose response relationships of (14C)-methylglucose transport conversion of (14C)-glucose to CO2 and total lipids, and lipolysis at 37 degrees C and pH 7.4 in adipocytes from obese patients before (n = 15) and after fasting for 10 days (n = 6). Studies of adipocytes from obese before fasting showed a significant reduction of insulin binding… Read More

Protein wasting due to acidosis of prolonged fasting

Hannaford, M. C., Leiter, L. A., Josse, R. G., Goldstein, M. B., Marliss, E. B., Halperin, M. L.
Am J Physiol 1982
Abstract

During a total fast in obese subjects, the daily rate of nitrogen excretion undergoes only a small further decline after 2 wk, the excretion rate being about 5 g N/day. At this time, ammonium and urea each constitute about one-half of this excretion. The purpose of this study was to consider two alternative hypotheses: first, that the near plateau in nitrogen excretion represents an… Read More

Differences in circulating gluconeogenic substrates during short-term fasting in men, women, and children

Haymond, M. W., Karl, I. E., Clarke, W. L., Pagliara, A. S., Santiago, J. V.
Metabolism 1982
Abstract

To determine whether the differences in fasting glucose responses in men, women and children could be related to differences in glucoregulatory hormone secretion or availability of circulating gluconeogenic substrates, 20 adults (10 men and 10 women) were fasted for 86 hr and 15 children (6.1 +/- 0.8 yr, mean +/- SE) were fasted for 30 hr. Circulating concentrations of glucose, ketone bodies,… Read More

Impact of hydrogen ion on fasting ketogenesis: feedback regulation of acid production

Hood, V. L., Danforth, E., Jr., Horton, E. S., Tannen, R. L.
Am J Physiol 1982
Abstract

To determine whether acid-base balance regulates hydrogen ion production, seven obese volunteers were given NaHCO3 and NH4Cl (2 mmol.kg-1.day-1) during two separate 7-day fasts. On days 5-7 plasma bicarbonate was lower in the NH4Cl fasts (14.0 +/- 1.4 mM) than in the NaHCO3 fasts (18.3 +/- 1.1 mM), while urine pH and net acid excretion did not differ. Acid production (acid excretion minus… Read More

Fasting in obesity: another cause of liver injury with alcoholic hyaline?

Capron, J. P., Delamarre, J., Dupas, J. L., Braillon, A., Degott, C., Quenum, C.
Dig Dis Sci 1982

Vegetarian fasting of obese patients: a clinical and biochemical evaluation

Sorbris, R., Aly, K. O., Nilsson-Ehle, P., Petersson, B. G., Ockerman, P. A.
Scand J Gastroenterol 1982
Abstract

The effects of vegetarian fasting were evaluated in 14 grossly obese patients who participated in a program comprising 5 weeks' fasting in a lactovegetarian health center. Before and after the fasting period the patients were hospitalized and put on a standardized weight-maintaining diet; at the health center they consumed vegetable juices containing less than 1 MJ and 3 g of protein per… Read More

Glucoregulation in obese man: effects of fasting, glucagon infusion, exercise and diabetes

Vranic, M., Steiner, G., Marliss, E., Zinman, B.
Int J Obes 1982