Fasting Literature Database

Biomedical publications about prolonged water-only fasting from 1881-1999

TrueNorth Health Foundation has meticulously curated an extensive database of historical literature on prolonged water-only fasting dating back to the late 19th century.

This collection serves as a valuable resource for researchers, healthcare professionals, and individuals interested in exploring early perspectives and research on the effects of water-only fasting in humans.

These publications span a range of topics, including physiological effects, clinical applications, and historical reviews, that offer insights into the rich history and evolving understanding of fasting as a therapeutic intervention.

The mechanism of the natriuresis of fasting

Sigler, M. H.
J Clin Invest 1975
Abstract

This study tests the hypothesis than obligatory cation coverage of metabolicaly generated anions is the mechanism for the sodium diuresis of fasting. Nine obese female subjects were equilibrated on a constant sodium and caloric intake and then fasted while sodium intake was maintianed. Particular activity schedule during fasting as during control. Consecutive 3-h increases in urinary sodium ,… Read More

Growth hormone secretion in starvation: a reassessment

Merimee, T. J., Fineberg, S. E.
J Clin Endocrinol Metab 1974

Glucose utilization by sweat glands during fasting in man

Benson, J. W., Jr., Buja, M. L., Thompson, R. H., Gordon, R. S., Jr.
J Invest Dermatol 1974

Effect of glucagon on amino acid and nitrogen metabolism in fasting man

Aoki, T. T., Muller, W. A., Brennan, M. F., Cahill, G. F., Jr.
Metabolism 1974

Nitrogen sparing induced by a mixture of essential amino acids given chiefly as their keto-analogues during prolonged starvation in obese subjects

Sapir, D. G., Owen, O. E., Pozefsky, T., Walser, M.
J Clin Invest 1974
Abstract

11 normal obese subjects were fasted for 33 days. In five, who served as controls, urine urea nitrogen excretion remained constant for 2 wk thereafter. The other six were given seven daily infusions containing 6-8 mmol each of the alpha-keto-analogues of valine, leucine, isoleucine, phenylalanine, and methionine (as sodium salts) plus 3-4 mmol each of the remaining essential amino acids (… Read More

The effect of adrenergic blockade on the glucagon responses to starvation and hypoglycemia in man

Walter, R. M., Dudl, R. J., Palmer, J. P., Ensinck, J. W.
J Clin Invest 1974
Abstract

In an attempt to ascertain whether the sympathetic nervous system modulates glucagon release in man during starvation and hypoglycemia, the influence of alpha and beta adrenergic blockade on glucagon responses was studied in young, healthy men subjected to fasting and insulin-induced hypoglycemia. Six volunteers fasted for 84 h on three separate occasions. Plasma immunoreactive glucagon (IRG… Read More