Fasting Literature Database

Biomedical publications about prolonged water-only fasting from 1881-1999

TrueNorth Health Foundation has meticulously curated an extensive database of historical literature on prolonged water-only fasting dating back to the late 19th century.

This collection serves as a valuable resource for researchers, healthcare professionals, and individuals interested in exploring early perspectives and research on the effects of water-only fasting in humans.

These publications span a range of topics, including physiological effects, clinical applications, and historical reviews, that offer insights into the rich history and evolving understanding of fasting as a therapeutic intervention.

Energy provision, tissue utilization, and weight loss in prolonged starvation

Runcie, J., Hilditch, T. E.
Br Med J 1974
Abstract

Daily weight loss measurements in 76 fasting, obese patients (58 females, 18 males) have shown a characteristic pattern of rapid loss initially (up to day 14) followed by a slower but uniform reduction in weight. There were significant sex differences. Measurements of tissue breakdown showed that the initial rapid weight loss was due to the continuing utilization by the nervous system of… Read More

Long-term follow-up of therapeutic starvation

Innes, J. A., Campbell, I. W., Campbell, C. J., Needle, A. L., Munro, J. F.
Br Med J 1974
Abstract

A total of 75 grossly obese patients were admitted to hospital for 80 episodes of prolonged starvation. Five took their own discharge within two weeks of admission and 12 defaulted from follow-up within 12 months of discharge. The others were all followed up for periods of 12 to 64 months. Altogether 39 episodes in 34 patients were classified as failures, eight as modified successes, and 16 as… Read More

The effect of starvation on the concentration and binding of thyroxine and triiodothyronine in serum and on the response to TRH

Portnay, G. I., O'Brian, J. T., Bush, J., Vagenakis, A. G., Azizi, F., Arky, R. A., Ingbar, S. H., Braverman, L. E.
J Clin Endocrinol Metab 1974

Therapeutic Starvation

Sievers, M. L., Hendrikx, M. E.
British Medical Journal 1974

Ketone-body production and oxidation in fasting obese humans

Reichard, G. A., Jr., Owen, O. E., Haff, A. C., Paul, P., Bortz, W. M.
J Clin Invest 1974
Abstract

Rates of plasma acetoacetate and total ketone-body production and oxidation to CO2 were determined by an isotope tracer technique in eight obese subjects undergoing progressive starvation. After a brief fast and under conditions of mild ketonemia and minimal ketonuria, rates of acetoacetate and total ketone-body production and oxidation were directly related to the increasing plasma… Read More

Homeostasis during fasting. II. Hormone substrate differences between men and women

Merimee, T. J., Fineberg, S. E.
J Clin Endocrinol Metab 1973

Albumin metabolism in fasting, obese subjects

Ballantyne, F. C., Smith, J., Fleck, A.
Br J Nutr 1973