Water-only Fasting Literature
A database of research publications dating back to 1881!

Latest Research

Author(s): Thackrey, E., Chen, J., Martino, C. R., Preda, V.
Publication: Nutrition
Publication Year: 2022

With the global rise in obesity and the metabolic syndrome, double diabetes is increasingly prevalent in patients with type 1 diabetes. This review investigated the effects of diet on weight management and metabolic outcomes in patients with double diabetes. MEDLINE, CENTRAL, EMBASE, PsycINFO, CINAHL, ERIC, and Web of Science databases were searched through September 2020. Population- or… Read More

Author(s): Hofer, S. J., Carmona-Gutierrez, D., Mueller, M. I., Madeo, F.
Publication: EMBO Mol Med
Publication Year: 2022

Age-associated diseases are rising to pandemic proportions, exposing the need for efficient and low-cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological levels. While nutrition and health are closely intertwined, our limited understanding of how diet precisely influences disease often precludes the medical use of specific dietary interventions. Caloric… Read More

Author(s): Myers, T, Saul, B, Karlsen, M, Beauchesne, A, Glavas, Z, Ncube, M, Bradley, R, Goldhamer, A
Publication: Cureus
Publication Year: 2022

The overconsumption of calorie-dense foods high in added salt, sugar, and fat is a major contributor to current rates of obesity, and methods to reduce consumption are needed. Prolonged water-only fasting followed by an exclusively whole-plant-food diet free of added salt, oil, and sugar may reduce the consumption of these hyper-palatable foods, but such effects have not been quantified.… Read More

Author(s): Bonjour, M., Gabriel, S., Valencia, A., Goldhamer, AC., Myers, TR.
Publication: Mary An Liebert INC
Publication Year: 2022

Psoriasis is an immune-mediated, inflammatory disease with a chronic relapsing nature that is characterized by increased skin proliferation and systemic manifestations.1 Topical and systemic medications manage inflammation and typically require long-term adherence to avoid relapse. 2 Here we present the case of a man with chronic, severe plaque psoriasis that regressed into remission after a… Read More

Author(s): Scharf, E., Zeiler, E., Ncube, M., Kolbe, K., Hwang, S. Y., Goldhamer, A., Myers, T. R.
Publication: Nutrients
Publication Year: 2022

(1) Background: Cardiometabolic disease, including insulin resistance, hyperlipidemia, and hypertension, are major contributors to adverse health outcomes. Fasting has gained interest as a nonpharmacological therapeutic adjunct for these disorders. (2) Methods: We conducted a prospective, single-center study on the effects of prolonged water-only fasting followed by an exclusively whole-plant-… Read More

Author(s): Stapel, B., Nosel, P., Heitland, I., Mahmoudi, N., Lanfermann, H., Kahl, K. G., Ding, X. Q.
Publication: J Psychiatr Res
Publication Year: 2021

Major depressive disorder (MDD) is characterized by dysregulation of stress systems and by abnormalities in cerebral energy metabolism. Stress induction has been shown to impact neurometabolism in healthy individuals. Contrarily, neurometabolic changes in response to stress are insufficiently investigated in MDD patients. Metabolic stress was induced in MDD patients (MDD, N = 24) and in… Read More

Author(s): Angoorani, P., Ejtahed, H. S., Hasani-Ranjbar, S., Siadat, S. D., Soroush, A. R., Larijani, B.
Publication: Nutr Metab (Lond)
Publication Year: 2021

BACKGROUND: Intermittent fasting has been reported to have positive effects on obesity, diabetes, cardiovascular diseases, hypertension, and several neurodegenerative diseases through different mechanisms such as alteration in the gut microbiota. This systematic review was conducted with the aim of providing an overview of the existing animal and human literature regarding the gut microbiota… Read More

Author(s): Berthelot, E., Etchecopar-Etchart, D., Thellier, D., Lancon, C., Boyer, L., Fond, G.
Publication: Nutrients
Publication Year: 2021

BACKGROUND: Fasting interventions have shown effectiveness in alleviating stress, anxiety and depressive symptoms. However, no quantitative analysis has been carried out thus far. The objective was to determine the effectiveness of fasting interventions on stress, anxiety and depression and if these interventions were associated with increased or decreased fatigue/energy. METHODS: Overall, 11… Read More

Author(s): Gabel, K., Cares, K., Varady, K., Gadi, V., Tussing-Humphreys, L.
Publication: Adv Nutr
Publication Year: 2021

Almost 40% of the adult population in the United States will be diagnosed with cancer in their lifetime. Diet is a modifiable factor which is known to affect cancer risk and recurrence. Yet, little is known about how diet influences cancer treatment outcomes. Intermittent fasting, characterized by periods of abstaining from foods and beverages alternated with periods of ad libitum intake, when… Read More

Author(s): Qian, J., Fang, Y., Yuan, N., Gao, X., Lv, Y., Zhao, C., Zhang, S., Li, Q., Li, L., Xu, L., Wei, W., Wang, J.
Publication: Aging Cell
Publication Year: 2021

Previous studies have shown that long-term light or moderate fasting such as intermittent fasting can improve health and prolong lifespan. However, in humans short-term intensive fasting, a complete water-only fasting has little been studied. Here, we used multi-omics tools to evaluate the impact of short-term intensive fasting on immune function by comparison of the CD45(+) leukocytes from… Read More