Water-only Fasting Literature
A database of research publications dating back to 1881!

Latest Research

Author(s): Wilson, R. L., Kang, D. W., Christopher, C. N., Crane, T. E., Dieli-Conwright, C. M.
Publication: Nutrients
Publication Year: 2021

Nutrition and exercise interventions are strongly recommended for most cancer patients; however, much debate exists about the best prescription. Combining fasting with exercise is relatively untouched within the oncology setting. Separately, fasting has demonstrated reductions in chemotherapy-related side effects and improved treatment tolerability and effectiveness. Emerging… Read More

Author(s): Bredella, M. A., Fazeli, P. K., Bourassa, J., Rosen, C. J., Bouxsein, M. L., Klibanski, A., Miller, K. K.
Publication: Bone
Publication Year: 2021

BACKGROUND: States of chronic overnutrition and undernutrition are both associated with impaired bone health and increased fracture risk but there are no data on bone microarchitecture following short-term controlled nutritional challenges. OBJECTIVE: The purpose of our study was to evaluate the impact of short-term high-caloric feeding and fasting on bone microarchitecture. We hypothesized… Read More

Author(s): Benau, E. M., Makara, A., Orloff, N. C., Benner, E., Serpell, L., Timko, C. A.
Publication: Curr Nutr Rep
Publication Year: 2021

PURPOSE OF REVIEW: The goal of this review was to provide an update on the literature examining how voluntary, temporary abstention from eating impacts cognitive function. RECENT FINDINGS: We evaluated peer-reviewed articles published between August 2013 and January 2021 that assessed adults, included a measure of cognitive functioning with neutral stimuli, and compared individuals in a fasted… Read More

Author(s): Hammoud, S., Kurdi, M., van den Bemt, B. J.
Publication: J Cardiovasc Pharmacol
Publication Year: 2021

ABSTRACT: Fasting has been frequently practiced for religious or medical purposes worldwide. However limited literature assesses the impact of different fasting patterns on the physiologic and cardiac-related parameters in patients with hypertension. This review aims to examine the effect of fasting on cardiovascular outcomes in hypertensive patients. Medline, Embase and Cochrane library were… Read More

Author(s): Bredella, M. A., Buckless, C., Fazeli, P. K., Rosen, C. J., Torriani, M., Klibanski, A., Miller, K. K.
Publication: Bone
Publication Year: 2021

BACKGROUND: Bone marrow adipose tissue (BMAT) plays a role in systemic energy metabolism and responds to nutritional changes. Chronic starvation as well as visceral adiposity are associated with BMAT accumulation. Two types of BMAT have been described which differ in anatomic location (proximal-regulated-rBMAT vs distal-constitutive-cBMAT) and composition (higher unsaturated lipids of cBMAT… Read More

Author(s): van Galen, K. A., Booij, J., Schrantee, A., Adriaanse, S. M., Unmehopa, U. A., Fliers, E., Schwartz, G. J., DiLeone, R. J., Ter Horst, K. W., la Fleur, S. E., Serlie, M. J.
Publication: Metabolism
Publication Year: 2021

BACKGROUND AND AIMS: Serotonergic and dopaminergic systems in the brain are essential for homeostatic and reward-associated regulation of food intake and systemic energy metabolism. It is largely unknown how fasting influences these systems or if such effects are altered in humans with obesity. We therefore aimed to evaluate the effects of fasting on hypothalamic/thalamic serotonin transporter… Read More

Author(s): Yang, X., Jiang, Y.
Publication: Clin Transl Med
Publication Year: 2021

Objective: As a protective response, during starvation organisms withdraw energy from growth and reproduction to focus on cellular maintenance. Cancer cells cannot undergo this differential response which has been theorized as an adjunct to improve both the effect of chemotherapy treatment and reduce treatment side effects. We sought to investigate the feasibility and effect of short-term… Read More

Author(s): Oglodek, E., Pilis, W.
Publication: Global Advances in Health and Medicine
Publication Year: 2021

Background: Water-only fasting (WF) is a practice used to improve and maintain health. Objective: The aim of the study was to show whether WF performed for 8 days may be a threat to the health and/or life of people undergoing this practice. Methods: Twelve middle-aged men participated in the study. During the 8-day WF, the subjects ate no food except for drinking mineral water. Before and… Read More

Author(s): Varkaneh Kord, H., M. Tinsley G, O. Santos H, Zand, H., Nazary, A., Fatahi, S., Mokhtari, Z., Salehi-Sahlabadi, A., Tan, S. C., Rahmani, J., Gaman, M. A., Sathian, B., Sadeghi, A., Hatami, B., Soltanieh, S., Aghamiri, S., Bawadi, H., Hekmatdoost, A.
Publication: Clin Nutr
Publication Year: 2021

BACKGROUND & AIMS: Fasting and energy-restricted diets have been evaluated in several studies as a means of improving cardiometabolic biomarkers related to body fat loss. However, further investigation is required to understand potential alterations of leptin and adiponectin concentrations. Thus, we performed a systematic review and meta-analysis to derive a more precise estimate of the… Read More

Author(s): Tang, L., Li, L., Bu, L., Guo, S., He, Y., Liu, L., Xing, Y., Lou, F., Zhang, F., Wang, S., Lv, J., Guo, N., Tong, J., Xu, L., Tang, S., Zhu, C., Wang, Z.
Publication: J Nutr
Publication Year: 2021

BACKGROUND: Dynamic orchestration of metabolic pathways during continuous fasting remains unclear. OBJECTIVE: We investigated the physiological effects of Bigu-style fasting and underlying metabolic reprogramming in healthy adults. METHODS: We conducted a 5-d Bigu trial in 43 healthy subjects [age 23.2 +/- 2.4 y; BMI (in kg/m2) 22.52 +/- 1.79]. Physiological indicators and body composition… Read More