Water-only Fasting Literature
A database of research publications dating back to 1881!

Latest Research

Author(s): van Galen, K. A., Booij, J., Schrantee, A., Adriaanse, S. M., Unmehopa, U. A., Fliers, E., Schwartz, G. J., DiLeone, R. J., Ter Horst, K. W., la Fleur, S. E., Serlie, M. J.
Publication: Metabolism
Publication Year: 2021

BACKGROUND AND AIMS: Serotonergic and dopaminergic systems in the brain are essential for homeostatic and reward-associated regulation of food intake and systemic energy metabolism. It is largely unknown how fasting influences these systems or if such effects are altered in humans with obesity. We therefore aimed to evaluate the effects of fasting on hypothalamic/thalamic serotonin transporter… Read More

Author(s): Johnson, D., Drenick, E. J.
Publication: Arch Intern Med
Publication Year: 1977

The weights of 207 morbidly obese patients were reduced via prolonged fasting. Half the patients fasted for close to two months, losing a mean of 28.2 kg; one fourth fasted for less than one month; and the other fourth fasted for more than two months, with a mean 41.4-kg loss. This latter group was heavier initially, and more than 50% attained near-normal weight. Patients with onset of… Read More

Author(s): Vingerhoeds, A. C., Kinderen, P. J. der, Thijssen, J. H., Schwarz, F.
Publication: J Endocrinol
Publication Year: 1970
Author(s): Drenick, E. J., Swendseid, M. E., Blahd, W. H., Tuttle, S. G.
Publication: JAMA
Publication Year: 1964
Author(s): Bak, A. M., Vendelbo, M. H., Christensen, B., Viggers, R., Bibby, B. M., Rungby, J., Jorgensen, J. O. L., Moller, N., Jessen, N.
Publication: PLoS One
Publication Year: 2018

Insulin resistance is a well-known physiological adaptation to prolonged fasting in healthy skeletal muscle. Obesity is associated with insulin resistance and metabolic inflexibility in skeletal muscle, and a pronounced increase in the risk of metabolic complications. Under the hypothesis that the metabolic traits of insulin resistance associated with prolonged fasting are different from… Read More

Author(s): Balazsi, I., Karadi, I., Somogyi, A., Jona, G., Romics, L.
Publication: Acta Med Hung
Publication Year: 1983

The HDL-cholesterol level was found to decrease during the first week of therapeutic starvation in hyperlipoproteinaemic (hypertriglyceridaemic), diabetic (non-insulin dependent) patients. The possible causes of the finding are discussed, and the view is expressed that the fall in HDL given no cause for discontinuing the caloric restriction or starvation as the therapeutic measures in obesity… Read More

Author(s): Scriba, P. C., Bauer, M., Emmert, D., Fateh-Moghadam, A., Hofmann, G. G., Horn, K., Pickardt, C. R.
Publication: Acta Endocrinol (Copenh)
Publication Year: 1979

UNLABELLED: The effects of total fasting for 31 +/- 10 days followed by re-alimentation with an 800 calorie diet on thyroid function, i.e. T4,T3,rT3,RT3U (resin T3 uptake), and TSH, and on TBG levels in serum were studied sequentially in obese hospitalized patients (N=18). Additionally, cortisol, growth hormone, prolactin, parathyrin and free fatty acids were followed as hormonal and metabolic… Read More

Author(s): Solter, M., Sekso, M.
Publication: Exp Clin Endocrinol
Publication Year: 1983

The relationship between altered glucose-insulin interaction in the hyperglycemic period of oral glucose tolerance test (oGTT) and impaired posthyperglycemic glucose homeostasis was studied in 9 obese females. They underwent 6-hour oGTT following 72-96 hour total fast, and the results of blood glucose, insulin, growth hormone, cortisol, glucagon and free fatty acids were compared to those of… Read More

Author(s): Pedersen, O., Hjollund, E., Sorensen, N. S.
Publication: Metabolism
Publication Year: 1982

We have studied (125I)-insulin binding and insulin dose response relationships of (14C)-methylglucose transport conversion of (14C)-glucose to CO2 and total lipids, and lipolysis at 37 degrees C and pH 7.4 in adipocytes from obese patients before (n = 15) and after fasting for 10 days (n = 6). Studies of adipocytes from obese before fasting showed a significant reduction of insulin binding… Read More

Author(s): Capron, J. P., Delamarre, J., Dupas, J. L., Braillon, A., Degott, C., Quenum, C.
Publication: Dig Dis Sci
Publication Year: 1982