Water-only Fasting Literature
A database of research publications dating back to 1881!
Fasting: molecular mechanisms and clinical applications
Publication:
Cell Metab
Publication Year:
2014
ISSN:
1932-7420 (Electronic) 1550-4131 (Linking)
DOI:
10.1016/j.cmet.2013.12.008
Abstract

Fasting has been practiced for millennia, but, only recently, studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism, and bolster cellular protection. In lower eukaryotes, chronic fasting extends longevity, in part, by reprogramming metabolic and stress resistance pathways. In rodents intermittent or periodic fasting protects against diabetes, cancers, heart disease, and neurodegeneration, while in humans it helps reduce obesity, hypertension, asthma, and rheumatoid arthritis. Thus, fasting has the potential to delay aging and help prevent and treat diseases while minimizing the side effects caused by chronic dietary interventions.

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